The iconic Maracana is the venue and the Selecao are favourites, though will be without the suspended Gabriel Jesus.
Jesus’s replacement Lucas Paqueta has stepped up, scoring crucial goals in the quarter-final and semi-final, and will start again alongside Neymar on Saturday night.
At the other end of the pitch, Manchester City’s Ederson continues to be preferred to Alisson in goal.
For Argentina, Messi is in fine form with four goals and five assists in six tournament games, with strike partner Lautaro Martinez looking to score for a fourth consecutive game.
Angel Di Maria, Nicolas Gonzalez and Alejandro Gomez are competing for the final spot in the front three.
Giovani Lo Celso, Rodrigo De Paul and Leandro Paredes will make up the midfield trio, though Cristian Romero is a doubt in defence.
Aston Villa goalkeeper Emiliano Martinez continues his rise to world prominence with another fine string of performances and will start the Final.
Here is how we predict the two sides will shape up in the Copa America Final…
Brazil vs Argentina predicted lineups
Brazil XI (4-2-3-1): Ederson; Danilo, Marquinhos, Silva, Sandro; Fred, Casemiro; Richarlison, Paqueta, Everton; Neymar
Argentina XI (4-3-3): E Martinez; Molina, Pezzella, Otamendi, Tagliafico; De Paul, Paredes, Lo Celso; Messi, L Martinez, Gomez
Goalkeepers: Alisson (Liverpool), Ederson (Manchester City), Weverton (Palmeiras).
Defenders: Emerson (Barcelona), Danilo, Alex Sandro (Juventus), Renan Lodi, Felipe (Atletico Madrid), Éder Militão (Real Madrid), Marquinhos (Paris Saint-Germain), Thiago Silva (Chelsea).
Midfielders: Casemiro (Real Madrid), Douglas Luiz (Aston Villa), Everton Ribeiro (Flamengo), Fabinho (Liverpool), Fred (Manchester United), Lucas Paquetã (Lyon).
Forwards: Everton (Benfica), Roberto Firmino (Liverpool), Gabriel Barbosa (Flamengo), Gabriel Jesus (Manchester City), Neymar (Paris Saint-Germain), Richarlison (Everton), Vinicius Junior (Real Madrid).
Goalkeepers: Franco Armani, Emiliano Martinez, Juan Musso and Agustin Marchesin
Defenders: Gonzalo Montiel, Nicolas Otamendi, German Pezzella, Nicolas Tagliafico, Lucas Martinez Quarta, Marcos Acuna, Lisandro Martinez, Nahuel Molina Lucero and Cristian Romero
Midfielders: Leandro Paredes, Giovani Lo Celso, Exequiel Palacios, Nicolas Gonzalez, Guido Rodriguez, Rodrigo De Paul, Alejandro Gomez, Angel Correa and Nicolas Dominguez
Forwards: Lionel Messi, Lautaro Martinez, Angel Di Maria, Joaquin Correa, Sergio Aguero and Julian Alvarez
Gabriel Jesus is suspended. All other players are available.
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